Decarbonization has become an imperative for the process industries, and energy efficiency has long been recognized an essential strategy. Unlike other approaches, energy efficiency inherently reduces operating costs while it decreases emissions, so it offers a positive return on investment, even without factoring in environmental benefits. The presentations in our Spring Energy Forum address a new DOE program to support energy efficiency and decarbonization in energy intensive industries, applications of automation and data analysis to improve energy performance, and, on a slightly different track, use of hydrogen in gas turbines as another approach to decarbonization.